ICD-10 Diagnosis Code C22.0

Liver cell carcinoma

Diagnosis Code C22.0

ICD-10: C22.0
Short Description: Liver cell carcinoma
Long Description: Liver cell carcinoma
This is the 2018 version of the ICD-10-CM diagnosis code C22.0

Valid for Submission
The code C22.0 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Neoplasms (C00–D48)
    • Malignant neoplasms of digestive organs (C15-C26)
      • Malignant neoplasm of liver and intrahepatic bile ducts (C22)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code C22.0 is grouped in the following Diagnostic Related Group(s) (MS-DRG V35.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Adenocarcinoma of liver
  • Combined hepatocellular carcinoma and cholangiocarcinoma
  • Fibrolamellar hepatocellular carcinoma
  • Liver cell carcinoma

Index of Diseases and Injuries
References found for the code C22.0 in the Index of Diseases and Injuries:

Table of Neoplasms

The code C22.0 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

The Tabular must be reviewed for the complete diagnosis code.

Neoplasm, neoplastic Malignant
CaInSitu Benign Uncertain

Information for Patients

Liver Cancer

Also called: Hepatocellular carcinoma

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Primary liver cancer starts in the liver. Metastatic liver cancer starts somewhere else and spreads to your liver.

Risk factors for primary liver cancer include

  • Having hepatitis B or C
  • Heavy alcohol use
  • Having cirrhosis, or scarring of the liver
  • Having hemochromatosis, an iron storage disease
  • Obesity and diabetes

Symptoms can include a lump or pain on the right side of your abdomen and yellowing of the skin. However, you may not have symptoms until the cancer is advanced. This makes it harder to treat. Doctors use tests that examine the liver and the blood to diagnose liver cancer. Treatment options include surgery, radiation, chemotherapy, or liver transplantation.

NIH: National Cancer Institute

  • Abdominal tap (Medical Encyclopedia)
  • After chemotherapy - discharge (Medical Encyclopedia)
  • Hepatocellular carcinoma (Medical Encyclopedia)
  • Liver metastases (Medical Encyclopedia)
  • Understanding Chemotherapy - NIH - Easy-to-Read (National Cancer Institute)
  • What to Know about External Beam Radiation Therapy - NIH - Easy-to-Read (National Cancer Institute)

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